Journal of Huntington's Disease: Landmark 10th Anniversary

Celebrating 10 Years of the Journal of Huntington's Disease

The issue of the Journal of Huntington’s Disease (JHD) published in March 2022 represents the 10th anniversary of the journal! To mark the occasion, the Editors-in-Chief Blair R. Leavitt, MD, and Leslie M. Thompson, PhD, have shared insights in the editorial about what they think makes JHD so special. View an extract below!

Also on this page, you can discover some of the top articles that have been published during the first 10 years of the journal.

In celebration of the 10th anniversary, all content in JHD Vol.11, Iss.1 is freely available for you to read, download, and share!


10 Years of the Journal of Huntington's Disease: Insights from the EICs

Hear about the lessons learned and successes shared during the first 10 years of JHD.
JHD 10th anniversary splash on a grey background

"We have come to appreciate that we are all important elements of a wonderfully multidisciplinary, collaborative, and diverse scientific and clinical community. We are proud of how Huntington's disease (HD) researchers have worked towards our common goals of increasing our understanding of HD, advancing HD care, and improving treatments for HD.

For the first 10 years of our journal's existence, it has fostered an inclusive and comprehensive publication policy aimed at distributing a diverse range of manuscripts on a wide variety of topics related to HD. We are committed to maintaining rigorous peer review and ensuring that JHD exclusively publishes technically sound and scientifically valid papers. We encourage HD researchers to publish negative results and to share any findings which will make significant contributions to scientific knowledge in this field. We do our best to serve the HD community by ensuring that papers submitted to JHD are reviewed as rapidly as possible and published in a timely fashion.

A key goal for the future is to provide authors with an even more efficient review process and to continue to reduce the length of time required to reach decisions for submissions. We applaud our many dedicated associate editors and reviewers, manuscript handling can sometimes be quite challenging, particularly during a pandemic. Finding appropriate reviewers takes valuable time. Evaluating scientific papers and delivering constructive and objective peer-reviews also takes valuable time. The dedication and amazing efforts that our various contributors to JHD have made over the years are the reason our journal has been able to grow, thrive, and succeed in difficult times.

We would like to thank all our amazing authors and readers for their support and contributions over the years.

Top 10 Cited Papers

View the top cited papers published during the journal's first 10 years.

Please peruse the journal’s 10 top cited papers* of the first 10 years:


  1. Oxidative Stress and Huntington's Disease: The Good, the Bad, and the Ugly – Amit Kumar and Rajiv R. Ratan | JHD 5:3 (2016), Review Article (Open Access)

  2. A transgenic minipig model of huntington’s disease – Monika Baxa, et al. | JHD 2:1 (2013), Research Article)

  3. Large genetic animal models of huntington’s disease – A. Jennifer Morton and David S. Howland | JHD 2:1 (2013), Research Article (Open Access)

  4. Antisense oligonucleotide-mediated correction of transcriptional dysregulation is correlated with behavioral benefits in the YAC128 mouse model of huntington’s disease – Lisa M. Stanek, et al. | JHD 2:2 (2013), Research Article 

  5. Unawareness of deficits in Huntington's disease – Emilia J. Sitek, et al. | JHD 3:2 (2014), Review Article (Open Access)

  6. Regional atrophy associated with cognitive and motor function in prodromal huntington disease – Elizabeth H. Aylward, et al. | JHD 2:4 (2013), Research Article

  7. Cognitive dysfunction in Huntington's disease: Humans, mouse models and molecular mechanisms – Albert Giralt, et al. | JHD 1:2 (2012), Review Article (Open Access)

  8. PBT2 reduces toxicity in a C. elegans model of polyQ aggregation and extends lifespan, reduces striatal atrophy and improves motor performance in the R6/2 mouse model of Huntington's disease – Cherny, Robert A. | JHD 1:2 (2012), Research Article (Open Access)

  9. Widespread heterogeneous neuronal loss across the cerebral cortex in Huntington's disease – Alissa L. Nana, et al. | JHD 3:1 (2014), Research Article 

  10. Fifteen years of clinical trials in Huntington's disease: A very low clinical drug development success rate – André M. Travessa, et al. | JHD 6:2 (2017), Research Article


*Data from Scopus (up to Feb 2022)

Top Viewed JHD Content

Check out the most popular articles published in JHD.

Please enjoy the journal’s 10 top viewed papers* during the first 10 years:


  1. Aquatherapy for Neurodegenerative Disorders – Alyson R. Plecash and Blair R. Leavitt | JHD 3:1 (2014), Review Article (Open Access)
  2. Physical Therapy and Exercise Interventions in Huntington’s Disease: A Mixed Methods Systematic Review – Nora E. Fritz, et al. | JHD 6:2 (2017), Research Article (Open Access)
  3. Huntington’s Disease Clinical Trials Corner: January 2019 – Filipe B. Rodrigues, et al. | JHD 8:1 (2019), Clinical Trials Corner (Openly Available)
  4. Cerebrospinal Fluid Biomarkers for Huntington’s Disease – Lauren M. Byrne and Edward J. Wild | JHD 5:1 (2016), Review Article (Open Access)
  5. Huntington’s Disease Clinical Trials Corner: April 2020 – Filipe B. Rodrigues and Edward J. Wild | JHD 9:2 (2020), Clinical Trials Corner (Openly Available)
  6. Survey of the Huntington’s Disease Patient and Caregiver Community Reveals Most Impactful Symptoms and Treatment Needs – Jennifer A. Simpson, et a. | JHD 5:4 (2016), Research Article (Openly Available)
  7. What do we know about Late Onset Huntington’s Disease? – Sai S. Chaganti, et a.l | JHD 6:2 (2017), Review Article (Open Access)
  8. Dysregulation of Corticostriatal Connectivity in Huntington’s Disease: A Role for Dopamine Modulation – Claudia Rangel-Barajas and George V. Rebec | JHD 5:4 (2016), Review Article (Open Access)
  9. Huntington’s Disease Pathogenesis: Two Sequential Components – Eun Pyo Hong, et al. | JHD 10:1 (2021), Review Article (Open Access)
  10. Clinical Management of Neuropsychiatric Symptoms of Huntington Disease: Expert-Based Consensus Guidelines on Agitation, Anxiety, Apathy, Psychosis and Sleep Disorders – Karen E. Anderson, et al. | JHD 7:4 (2018), Research Article (Open Access)


*Data from the IOS Press Content Library (up to Feb 2022)