International Journal of Risk & Safety in Medicine

Patient Safety - Pharmacovigilance - Liability



33, 4 issues

Latest issue

33:S1 online 02 December 2022

Next issue

34:1 scheduled for March 2023

Back volumes

From volume 1, 1990

ISSN print


ISSN online


Aims & Scope

The International Journal of Risk and Safety in Medicine is concerned with rendering the practice of medicine as safe as it can be; that involves promoting the highest possible quality of care, but also examining how those risks which are inevitable can be contained and managed. This is not exclusively a drugs journal. Recently it was decided to include in the subtitle of the journal three items to better indicate the scope of the journal, i.e. patient safety, pharmacovigilance and liability and the Editorial Board was adjusted accordingly. For each of these sections an Associate Editor was invited. We especially want to emphasize patient safety. Our journal wants to publish high quality interdisciplinary papers related to patient safety, not the ones for domain specialists. For quite some time we have also been devoting some pages in every issue to what we simply call WHO news. This affinity with WHO underlines both the International character of the journal and the subject matter we want to cover. Basic research, reports of clinical experience and overviews will all be considered for publication, but since major reviews of the literature are often written at the invitation of the Editorial Board it is generally advisable to consult with the Editor in advance. Submission of news items will be appreciated, as will be the contribution of letters on topics which have been dealt with in the journal.

Editorial Board


I. Ralph Edwards
Professor in Medicine
Uppsala Monitoring Centre



Marie Lindquist
WHO Collaborating Centre for
International Drug Monitoring



Former Editor-in-Chief

C.J. van Boxtel

Founding Editor

M.N.G. Dukes

Associate Editors

Carlo Bottari
Pharmaceuticals Policy and Law
University of Bologna
Bologna, Italy

Maxine Gossell-Williams
Pharmacology and Pharmacovigilance
The University of the West Indies at Mona
Kingston, Jamaica

Federico Laus
Pharmaceuticals Policy and Law
University of Bologna
Bologna, Italy

Mecit Can Emre Simsekler
Patient Safety
Boston Children’s Hospital
Boston, MA, USA

Liliya E. Ziganshina
Clinical Pharmacology and Evidence-Based Medicine
Russian Medical Academy for Continuing Professional Education (RMANPO) 
Moscow, Russian Federation

Editorial Board

Peter R. Breggin
Private Practice of Psychiatry
Clinical Psychopharmacology and Forensics
Ithaca, NY, USA

Elliot Brown
Medicine, Clinical Pharmacology and Regulatory Affairs
Elliot Brown Consulting Ltd
Leeds, UK

Rebecca Chandler
Pharmacovigilance, Infectious Diseases and Vaccines
Uppsala Monitoring Centre
Uppsala, Sweden

Andrzej Czarnecki
Pharmacovigilance and Internal Medicine
Eli Lilly and Company
Windlesham, UK

Edzard Ernst
Complementary Medicine
University of Exeter
Exeter, UK

Ulrich Hagemann
Drug Commission of the German Medical Association
Berlin, Germany

Rokuro Hama
Internal Medicine and Patient Safety
Japan Institute of Pharmacovigilance
Osaka, Japan

Ambrose Isah
Medicine and Clinical Pharmacology
University of Benin
Benin, Nigeria

Jesse Lyle Bootman
Pharmaceuticals Policy and Law
Tabula Rasa Health Care
Moorestown, NJ, USA

Donald Harvey Marks
Internal Medicine and Microbiology
University of Pittsburgh
Pittsburgh, PA, USA

John McEwen
Pharmacovigilance and Neurology
Therapeutic Goods Administration
Canberra, Australia

Priscilla Patricia Nyambayo
Pharmacovigilance and Clinical Trials
Munyaradzi Medicines Control
Authority of Zimbabwe
Harare, Zimbabwe

Emmanuel Okoro
Medicine and Clinical Pharmacology
Covenant University Ota
Ota, Nigeria

Abimbola Olowofela-Opadeyi
Clinical Pharmacology and Therapeutics
University of Benin
Benin, Nigeria

Eugène van Puijenbroek
University Groningen
Groningen, The Netherlands

Elena Rocca
Philosophy of Science and Health Care
NMBU University
Ås, Norway

Mulugeta Russom
Eritrean Pharmacovigilance Centre
Asmara, Eritrea

Ruth Savage
Clinical Pharmacology and Epidemiology
University of Otago
Christchurch, New-Zealand

Anders Sundström
Karolinska Institutet
Solna, Sweden

Michael Tatley
Pharmacovigilance, Public Health and Vaccines
Otago University
Dunedin, New Zealand

Adam Urato
Maternal and Fetal Medicine
MetroWest Medical Center
Framingham, MA, USA

Mauro Venegoni
Internal Medicine and Pharmacovigilance
University of Verona
Verona, Italy

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1. Place citations as numbers in square brackets in the text. All publications cited in the text should be presented in a list of references following the text of the manuscript. Only articles published or accepted for publication should be listed in the reference list. Submitted articles can be listed in the text as (author(s), unpublished data).

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3. References must be listed in Vancouver style:

[1] Rose ME, Huerbin MB, Melick J, Marion DW, Palmer AM, Schiding JK, Kochanek PM, Graham SH. Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury. Brain Res. 2002; 935(12): 406.
[2] Murray PR, Rosenthal KS, Kobayashi GS, Pfaller MA. Medical microbiology. 4th ed. St. Louis: Mosby; 2002.
[3] Berkow R, Fletcher AJ, editors. The Merck manual of diagnosis and therapy. 16th ed. Rahway (NJ): Merck Research Laboratories; 1992.
[4] Meltzer PS, Kallioniemi A, Trent JM. Chromosome alterations in human solid tumors. In: Vogelstein B, Kinzler KW, editors. The genetic basis of human cancer. New York: McGrawHill; 2002. p. 93113.
[5] Canadian Cancer Society [homepage on the Internet]. Toronto: The Society; 2006 [updated 2006 May 12; cited 2006 Oct 17]. Available from:

Footnotes should only be used if absolutely essential. In most cases it is possible to incorporate the information in the text.
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Peer Review Policy

The International Journal of Risk & Safety in Medicine is a peer-reviewed journal. Articles submitted to the journal undergo a single-blind peer review process. This means that the identity of the authors is known to the reviewers but the identity of the reviewers is not communicated to the authors. Please visit our reviewer guidelines for further information about how to conduct a review.

All submitted manuscripts are subjected to initial appraisal by the Editors-in-Chief and, if found suitable for further consideration, to rigorous peer review by independent, anonymous expert referees. Reasons to reject a paper in the pre-screening process could for example be that the work does not fall within the aims and scope, the writing is of poor quality, the instructions to authors were not followed or the presented work is not novel.

Papers deemed suitable to be reviewed will be assigned to a handling editor. The handling editor will then invite reviewers to comment on the work and might consider inviting the reviewers suggested by the author(s). Editors and reviewers are asked to excuse themselves from reviewing a submission if a conflict of interest makes them unable to make an impartial scientific judgment or evaluation. Conflicts of interest include but are not limited to: collaboration with the authors in the past three years; any professional or financial affiliations that may be perceived as a conflict of interest; a history of personal differences with the author(s).

As a standard policy, decisions are based on three reviews, in some specific circumstances a minimum of two reviews may be deemed sufficient to make a decision on a paper. The Editors-in-Chief strive to ensure a typical turnaround time of three months.

Reviewers are asked to judge a paper on at least:

  • Logical, concise ordering of ideas
  • Use of sound research methods
  • Adequacy of documentation    
  • Material has good applied use in the field    
  • Readability and interest level

Based on the received reviews the handling editor will propose to the Editors-in-Chief a recommendation:

  1. Accept article as submitted
  2. Accept article revision by the author according to suggestions made in review
  3. Revise and resubmit
  4. Reject
  5. Consider for another issue/publication

They mean the following:

  1. The manuscript is suitable for publication and only requires minor polishing; thus, no further reviews are requested.
  2. The authors are required to make moderate changes to their manuscript. The manuscript becomes acceptable for publication if the changes proposed by the reviewers and editors are successfully addressed. The revised manuscript will be examined by the Editors-in-Chief and possibly sent back to all (or a selection of) reviewers for a second round of reviews. Authors are requested to provide a letter to the reviewers detailing the improvements made for the resubmission.
  3. In its current form, the manuscript is not suitable for publication. A resubmission would require substantial revisions and is only encouraged in special cases. The resubmitted manuscript will be considered as a new submission.
  4. The manuscript is rejected as it is deemed to be out of scope, not relevant, or not meeting the journal’s quality standards in terms of significance, novelty, and/or presentation.
  5. The manuscript is rejected as it is deemed to be better suited for a different journal or publication.

Authors are notified by the Editors-in-Chief, whose decision is final.

Former Editor-in-Chief of The International Journal of Risk & Safety in Medicine, Prof. Dr. Christoffel Jos van Boxtel, has passed away on the 23rd of January 2020. He will be greatly missed. We have published an In Memoriam, which can be found here. We are very pleased to announce that the Editor-in-Chief of The International Journal of Risk & Safety in Medicine, I. Ralph Edwards, was awarded the Honorary Doctor of Science Degree by the University of Benin, Nigeria in 2020. We congratulate him on this achievement. For more information, please see here.

The International Journal of Risk & Safety in Medicine is putting out a call for papers on the following topics: Evaluations of the risks versus benefits of any medical intervention Understanding and communication of vaccine risks Understanding and communication of uncertainty in medicines Risk and harm of medical care to clinical care practitioners

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Antibiotic misuse and improper practices in India: Identifying the scope to improve through a narrative review
Shruti Kulkarni, Brinal Pereira

Safety culture in emergency medicine: An exploratory qualitative study
Erika Borkoles, Muhammad Ahmed Alshyyab, Rania Ali Albsoul, Frances B. Kinnear, Gerard FitzGerald

Restoring the two pivotal fluoxetine trials in children and adolescents with depression
David Healy, Peter C. Gøtzsche

Adaptation and implementation of the Batz guide for bedside advocacy in two hospitals
Dolores Machiavello, Viviana Rodríguez, Cintia Spira, Juan Ruiz, Fernando Canteros, Javier Roberti, María Belizán, Ezequiel García-Elorrio

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