Cancer Biomarkers

Impact Factor


33-35, 12 issues

Latest issue

32:4 online 07 December 2021

Next issue

33:1 scheduled for January 2022

Back volumes

From volume 1, 2005

ISSN print


ISSN online


Aims & Scope

Concentrating on molecular biomarkers in cancer research, Cancer Biomarkers publishes original research findings (and reviews solicited by the editor) on the subject of the identification of markers associated with the disease processes whether or not they are an integral part of the pathological lesion. The disease markers may include, but are not limited to, genomic, epigenomic, proteomics, cellular and morphologic, and genetic factors predisposing to the disease or indicating the occurrence of the disease. Manuscripts on these factors or biomarkers, either in altered forms, abnormal concentrations or with abnormal tissue distribution leading to disease causation will be accepted.

Editorial Board


Sudhir Srivastava, PhD, MPH
c/o IOS Press, Inc.
6751 Tepper Drive, Clifton
Fax: +1 703 830 2300

Associate Editors

Karen S. Anderson, MD, PhD
Biodesign Institute, Arizona State University, Tempe, AZ

Surinder K. Batra, PhD
University of Nebraska Medical Center, Omaha, NE

Ajay Goel, PHD, AGAF
Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, CA

William E. Grizzle, MD, PhD
University of Alabama at Birmingham, Birmingham, AL

Sam Hanash, MD, PhD
University of Texas MD Anderson Cancer Center, Houston, TX

Kazufumi Honda, PhD
Nippon Medical School, Tokyo

Anna Lokshin, PhD
University of Pittsburgh Cancer Institute, Pittsburgh, PA

Attila T. Lorincz, PhD
Wolfson Institute of Preventive Medicine, Queen Mary University of London, London
United Kingdom

Karin D. Rodland, PhD
Pacific Northwest National Laboratory, Richland, WA

Zhen Zhang, PhD
Johns Hopkins University School of Medicine, Baltimore, MD

Regional Associate Editors for China, Central China

Tony Hu, PhD
Arizona State University

Lei Wang, PhD
National Center for Human Genetic Resources

Heng Xie, MD, MPH, PhD
Shenzen Salubris Pharmaceuticals

Regional Associate Editors for China, East China

Liming Cheng, PhD
Tongji Medical College

Sidney W. Fu, MD, PhD
The George Washington University School of Medicine and Health Sciences

Regional Associate Editors for China, North China

Xiaohong Han, MD
Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs

YingYing Lu, MD, PhD
Comprehensive Liver Cancer Center

Regional Associate Editors for China, South China

Lei Zheng, MD, PhD
Southern Medical University, Guangzhou

Regional Associate Editors for China, West China

Li Jiang, MD, PhD
Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital

Statistical Editors

Ziding Feng, PhD
Fred Hutchinson Cancer Research Center, Seattle, WA

Steven J. Skates, PhD
Massachusetts General Hospital, Harvard Medical School, Boston, MA

Editorial Board

Michael B. Atkins, MD
Georgetown University Medical Center

Timothy M. Block, PhD
Baruch S. Blumberg Institute

Roger Chammas, MD, PhD
University of São Paulo, Instituto do Câncer
Claudia Bessa P. Chaves, MD, PhD
Brazilian National Cancer Institute

David Chia, PhD
University of California

Arul M. Chinnaiyan, MD, PhD
University of Michigan

Miral Dizdaroglu, PhD
National Institute of Standards and Technology

Amit Gupta, MBBS MS, MBA
All India Institute of Medical Sciences

Michael Hollingsworth, PhD
University of Nebraska Medical Center

Ann M. Killary, PhD
University of Texas MD Anderson Cancer Center

Joshua LaBaer, PhD
Harvard University

Aija Linē, PhD
Latvian Biomedical Research and Study Centre

Alvin Y. Liu, PhD
University of Washington

Zvi Livneh
Weizmann Institute of Science

Cesar Lopez-Camarillo, PhD
Universidad Autonoma de la Ciudad de Mexico

Bramanandam Manavathi, PhD
University of Hyderabad
Jeffrey R. Marks, PhD
Duke University

Stephen J. Meltzer, MD
Johns Hopkins University

Patrick Nasarre, PhD
Medical University of South Carolina

Norbert Nass, PhD
Otto-von-Guericke-University Magdeburg

Peng, Cheng, PhD
University of Queensland

Wenxin Qin, PhD
Shanghai Cancer Institute

William N. Rom, MD, MPH
Sol and Judith Bergstein Foundation
John Semmes, PhD
Eastern Virginia Medical School

David Sidransky, MD
Johns Hopkins University
Sanford Stass, MD
University of Maryland School of Medicine

Michael A. Tainsky, PhD
Wayne State University School of Medicine

Sebastien Taurin, PhD
Arabian Gulf University


Author Guidelines


By submitting my article to this journal, I agree to the Author Copyright Agreement, the IOS Press Ethics Policy, and the IOS Press Privacy Policy.

Authors are requested to submit their manuscript electronically to the journal’s editorial management system.

The manuscript should be uploaded as one file with tables and figures included. Please use the journal's manuscript template. Acceptable file formats include Word document or PDF files; in case of large file size, a zip file can be uploaded.

Important note: The journal does not accept submissions from authors using nondescript, anonymous, email addresses (e.g.,,,,,,, etc.).

Required files
A .pdf file of the article is required along with the source files of the text, such as MsWord or LaTeX. If using LaTeX, please use the standard article.sty as a style file and also send a .pdf version of the LaTeX file as well as separate files of all figures (if any). See "Preparation of manuscripts" for the required file formats. LaTeX packages should be compiled into .zip or .rar files.

Publication Fee
Papers submitted to Cancer Biomarkers that are accepted for publication will be subject to a publication charge. The publication fee for Cancer Biomarkers is currently US$480 / €400 (excl. VAT if applicable).

Corresponding authors from countries with low-income economies may be eligible for a waiver of the publication fee. The eligible countries are defined by the Hinari project ( Fees are waived on a case-by-case basis.

The corresponding author should notify the journal of their inability to pay the publication fee upon submission of the article, otherwise the request will not be evaluated. Invited articles may be excluded from paying a publication fee. When an article is accepted for publication in the journal, the acceptance letter to the corresponding author will include a link to the journal’s online payment form. Authors can pay the fee by credit card or through bank transfer. After payment of the publication fee, the paper will be taken into production by the IOS Press production office. Payment of the publication fee must be received before an article is published in the journal.

Color figures
It is possible to have figures printed in color, provided the cost of their reproduction is paid for by the author. See Preparation of Manuscripts for the required file formats.

Open access option
IOS Press offers authors open access options for all its journals. If you opt for open access, the article will be freely available from the moment it is published, also in the pre-press module. Article processing charges are paid in the form of an open access fee. Authors will receive an open access order form upon acceptance of their article. Open access is entirely optional.

For more information about the OA options and licenses available in the IOS Press Open Library, and also to check if there are any institutional agreements that you might be eligible for.


Organization of the paper and style of presentation
Manuscripts must be written in English. Authors whose native language is not English are recommended to seek the advice of a native English speaker, if possible, before submitting their manuscripts.

Peerwith offers a language and copyediting service to all scientists who want to publish their manuscript in scientific peer-reviewed periodicals and books.

Manuscripts should be prepared with wide margins and double spacing throughout, including the abstract, footnotes and references. Every page of the manuscript, including the title page, references, tables, etc., should be numbered. However, in the text no reference should be made to page numbers; if necessary, one may refer to sections. Try to avoid the excessive use of italics and bold face.
Manuscripts should be organized in the following order:

  • Title page
  • Body of text (divided by subheadings)
  • Acknowledgements
  • Author contributions
  • References
  • Tables
  • Figure captions
  • Figures

Headings and subheadings should be numbered and typed on a separate line, without indentation.

SI units should be used, i.e., the units based on the metre, kilogramme, second, etc.

Title page
The title page should provide the following information:

  • Title (should be clear, descriptive and not too long)
  • Name(s) of author(s) without abbreviation; please indicate who is the corresponding author. Note that no authors will be added or removed post submission, unless the journal editor and all co-authors are informed and are in agreement to this change.
  • Full affiliation(s)
  • Present address of author(s), if different from affiliation
  • Complete address of the corresponding author, including tel. no., fax no., e-mail address and ORCID ID
  • Abstract
  • Keywords.

The abstract should be clear, descriptive, self-explanatory and not longer than 200 words, it should also be suitable for publication in abstracting services.
The abstract for research papers should follow the “structured abstract” format. Section labels should be in bold uppercase letters followed by a colon, and each section will begin on a new line.

Materials and Methods
Experimental subjects
When human subjects are used, manuscripts must be accompanied by a statement that the experiments were undertaken with the understanding and written consent of each subject, and that the study conforms with The Code of Ethics of the World Medical Association (Declaration of Helsinki), printed in the British Medical Journal (18 July 1964).

When experimental animals are used, the Materials and methods section must briefly but explicitly state measures which were taken to minimize pain or discomfort, e.g. type and dose of anaesthetic used. Experiments should be carried out in accordance with the European Communities Council Directive of 24 November 1986 (86/609/EEC) or with the Guidelines laid down by the NIH in the US, available from the Office of Laboratory Animal Welfare, National Institutes of Health, Department of Health and Human Services, RKLI, Suite 360, MSC 7982, 6705 Rockledge Drive, Bethesda, MD 20892-7982, or online ( .htm#pol) regarding the care and use of animals for experimental procedures.

All studies using human or animal subjects should include an explicit statement in the Materials and Methods section identifying the review and approval committee for each study. Editors reserve the right to reject papers if there is doubt whether appropriate procedures have been used.

This section should contain all acknowledgments, including any funding source to the research.

Author contributions
For every author, his or her contribution to the manuscript needs to be provided using the following categories:
Interpretation or analysis of data:
Preparation of the manuscript:
Revision for important intellectual content:


Place citations as numbers in square brackets in the text. All publications cited in the text should be presented in an alphabetical list of references at the end of the manuscript in the following style:

[1] B. Newman and E.T. Liu, Perspective on BRCA1, Breast Disease 10 (1998), 3-10.
[2] D.F. Pilkey, Happy conservation laws, in: Neural Stresses, J. Frost, ed., Controlled Press, Georgia, 1995, pp. 332-391.
[3] E. Wilson, Active vibration analysis of thin-walled beams, Ph.D. Dissertation, University of Virginia, 1991.

Footnotes should only be used if absolutely essential. In most cases it is possible to incorporate the information in the text.

If used, they should be numbered in the text, indicated by superscript numbers and kept as short as possible.

Number as Table 1, Table 2 etc., and refer to all of them in the text.
Each table should be provided on a separate page of the manuscript. Tables should not be included in the text.
Each table should have a brief and self-explanatory title.
Column headings should be brief, but sufficiently explanatory. Standard abbreviations of units of measurement should be added between parentheses.
Vertical lines should not be used to separate columns. Leave some extra space between the columns instead.
Any explanations essential to the understanding of the table should be given in footnotes at the bottom of the table.

Number figures as Fig. 1, Fig. 2, etc. and refer to all of them in the text.

Each figure should be provided on a separate sheet. Figures should not be included in the text.

Color figures can be included in the print version, provided the cost of their reproduction is paid for by the author. The online version has no extra charges for color figures.

For the file formats of the figures please take the following into account:
- Line art should be have a minimum resolution of 600 dpi, save as EPS or TIFF
- Grayscales (incl. photos) should have a minimum resolution of 300 dpi (no lettering), or 500 dpi (when there is lettering); save as tiff
- Do not save figures as JPEG, this format may lose information in the process
- Do not use figures taken from the Internet, the resolution will be too low for printing
- Do not use color in your figures if they are to be printed in black & white, as this will reduce the print quality (note that in software often the default is color, you should change the settings)
- For figures that should be printed in color, please send a CMYK encoded EPS or TIFF

Figures should be designed with the format of the page of the journal in mind. They should be of such a size as to allow a reduction of 50%.

On maps and other figures where a scale is needed, use bar scales rather than numerical ones, i.e., do not use scales of the type 1:10,000. This avoids problems if the figures need to be reduced.

Each figure should have a self-explanatory caption. The captions to all figures should be typed on a separate sheet of the manuscript.

Photographs are only acceptable if they have good contrast and intensity.


Copyright of your article
Authors submitting a manuscript do so on the understanding that they have read and agreed to the terms of the IOS Press Author Copyright Agreement.

Quoting from other publications
An author, when quoting from someone else's work or when considering reproducing figures or table from a book or journal article, should make sure that he is not infringing a copyright. Although in general an author may quote from other published works, he should obtain permission from the holder of the copyright if he wishes to make substantial extracts or to reproduce tables, plates or other figures. If the copyright holder is not the author of the quoted or reproduced material, it is recommended that the permission of the author should also be sought. Material in unpublished letters and manuscripts is also protected and must not be published unless permission has been obtained. Submission of a paper will be interpreted as a statement that the author has obtained all the necessary permission. A suitable acknowledgement of any borrowed material must always be made.


The corresponding author will receive a PDF proof and is asked to check this proof carefully (the publisher will execute a cursory check only). Corrections other than printer's errors, however, should be avoided. Costs arising from such corrections will be charged to the authors.


How to order reprints, a PDF file, journals, or IOS Press books
The corresponding author of a contribution to the journal will receive a complimentary PDF Author’s Copy of the article, unless otherwise stated. This PDF copy is watermarked and for personal use only. A free PDF copy will not be provided for conference proceedings and abstract issues. An order form for a PDF file without watermark, reprints or additional journal copies will be provided along with the PDF proof.

If you wish to order reprints of an earlier published article, please contact the publisher for a quotation. IOS Press, Fax: +31 20 687 0019. Email:

An author is entitled to 25% discount on IOS Press books. See Author's discount (25%) on all IOS Press book publications.


Authors of published articles (non-prepress, final articles) will be contacted by Kudos. Kudos is a service that helps researchers maximize the impact and visibility of their research. It allows authors to enrich their articles with lay metadata, add links to related materials and promote their articles through the Kudos system to a wider public. Authors will receive no more than three emails: one invitation and a maximum of two reminders to register for the service and link the published article to their profile. Using and registering for Kudos remains entirely optional. For more information, please have a look at our authors section.


Would you like some pointers on how to help your research achieve a wider reach and greater impact? Please consult our Promotional Toolkit for Authors for tips.

Abstracted/Indexed in

Academic Search
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Chemical Abstracts Service (CAS)
Elsevier BIOBASE
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SciVerse Scopus
Ulrich's Periodicals Directory
Web of Science: Biological Abstracts
Web of Science: BIOSIS Previews
Web of Science: Journal Citation Reports/Science Edition
Web of Science: Science Citation Index Expanded (SciSearch®)

Peer Review Policy

Cancer Biomarkers is a peer-reviewed journal. Articles submitted to the journal undergo a single blind peer review process. This means that the identity of the authors is known to the reviewers but the identity of the reviewers is not communicated to the authors.

All submitted manuscripts are subjected to initial appraisal by the Editor-in-Chief and, if found suitable for further consideration, to rigorous peer review by independent, anonymous expert referees. Reasons to reject a paper in the pre-screening process could for example be that the work does not fall within the aims and scope, the writing is of poor quality, the instructions to authors were not followed or the presented work is not novel.

Papers deemed suitable to be reviewed will be assigned to a handling editor. The handling editor will then invite reviewers to comment on the work. They might consider inviting the reviewers suggested by the author or not. Editors and reviewers are asked to excuse themselves from reviewing a submission if a conflict makes them unable to make an impartial scientific judgment or evaluation. Conflicts of interest include but are not limited to: collaboration with the authors in the past three years; any professional or financial affiliations that may be perceived as a conflict of interest; a history of personal differences with the author(s).

As a standard policy, decisions are based on three reviews, in some specific circumstances a minimum of two reviews may be deemed sufficient to make a decision on a paper. The Editor-in-Chief strives to ensure a typical turnaround time of 3 months.

Reviewers are asked to judge a paper on at least:

  • Significance to field
  • Relevance to journal
  • Methodology
  • Data analysis
  • Literature review
  • Writing style/clarity

Based on the received reviews the handling editor will propose to the Editor-in-Chief a recommendation:

  1. Accept
  2. Minor revisions required
  3. Major revisions required
  4. Reject

They mean the following:

  1. The manuscript is suitable for publication and only requires minor polishing; thus, no further reviews are requested.
  2. The authors are required to make moderate changes to their manuscript. The manuscript becomes acceptable for publication if the changes proposed by the reviewers and editors have been addressed satisfactorily. The revised manuscript will be examined by the Editor in Chief and possibly sent back to all (or a selection of) reviewers for a second round of reviews. Authors are requested to provide a letter to the reviewers detailing the improvements made for the resubmission.
  3. The manuscript cannot be accepted for publication in its current form. However, a major revision addressing all issues raised by the reviewers may be acceptable for publication. The revised manuscript will undergo a full second round of review. Authors are requested to provide a letter to the reviewers detailing the improvements made for the resubmission.
  4. The manuscript is rejected as it is deemed to be out of scope, not relevant, or not meeting the journal’s quality standards in terms of significance, novelty, and/or presentation.

Authors are notified by the Editor-in-Chief, whose decision is final.

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Journal Impact Factor – The latest Journal Citation Reports sees CBM's Impact Factor having risen to 4.388 (Source Clarivate, 2021). The journal sits in the second quartile for Oncology journals. 

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