Biomedical Spectroscopy and Imaging

Volume

11, 4 issues

Latest issue

10:1-2 online 17 December 2021

Next issue

10:3 scheduled for March 2022

Back volumes

From volume 1, 2012

ISSN print

2212-8794

ISSN online

2212-8808

Aims & Scope

Biomedical Spectroscopy and Imaging (BSI) is a multidisciplinary journal devoted to the timely publication of basic and applied research that uses spectroscopic and imaging techniques in different areas of life science including biology,  biochemistry, biotechnology, bionanotechnology,  environmental science, food science, pharmaceutical science, physiology and medicine.   Scientists are encouraged to submit their work for publication in the form of original articles, brief communications, rapid communications, reviews and mini-reviews.

The journal is dedicated to providing a single forum for experts in spectroscopy and imaging as applied to biomedical problems, and also for life scientists who use these powerful methods for advancing their research work.  BSI aims to promote communication, understanding and synergy across the diverse disciplines that rely on spectroscopy and imaging. It also encourages the submission of articles describing development of new devices and technologies, based on spectroscopy and imaging methods, for application in diverse areas including medicine, biomedical science, biomaterials science, environmental science, pharmaceutical science, proteomics, genomics, metabolomics, microbiology, biotechnology, genetic engineering, nanotechnology, etc.

Techniques covered include, but are not limited, to the following:

• Vibrational Spectroscopy (Infrared, Raman, Teraherz)
• Circular Dichroism Spectroscopy
• Magnetic Resonance Spectroscopy (NMR, ESR)
• UV-vis Spectroscopy
• Mössbauer Spectroscopy
• X-ray Spectroscopy (Absorption, Emission, Photoelectron, Fluorescence)
• Neutron Spectroscopy
• Mass Spectroscopy
• Fluorescence Spectroscopy
• X-ray and Neutron Scattering
• Differential Scanning Calorimetry
• Atomic Force Microscopy
• Surface Plasmon Resonance
• Magnetic Resonance Imaging
• X-ray Imaging
• Electron  Imaging
• Neutron Imaging
• Raman Imaging
• Infrared Imaging
• Terahertz  Imaging
• Fluorescence Imaging
• Near-infrared spectroscopy

Editorial Board

Editor-in-Chief

Prof. Parvez I. Haris, PhD, FRSC, FRSPH  
Faculty of Health & Life Sciences
De Montfort University
The Gateway
Leicester, LE1 9BH
UK
Tel.: +44 (0)116 250 6306
Email: bsi@iospress.com

Editor for Asia

Prof. Z. Yu
Department of Chemistry
Hetian Building
Tsinghua University

Beijing 100084
China
Tel.: +86 10 627 8138
Email: yuzhw@mail.tsinghua.edu.cn

Social Media Editor

Dr. Eid Brima
Department of Chemistry
College of Science
King Khalid University
Abha 61413
Saudi Arabia

Editorial Board

Ahmed Aamouche
Université Cadi Ayyad, Morocco

Alessandro Alimonti
Italian National Institute for Health
Rome, Italy

Y. Asakawa
Tokushima Bunri University
Tokushima, Japan

Malgorzata Baranska
Jagiellonian University
Krakow, Poland

Sevgi Bayari
Hacetepe University
Ankara, Turkey

J. Sabine Becker
Research Center Juelich
Juelich, Germany

Alper Bozkurt
Department of Electrical and Computer Engineering
North Carolina State University
Raleigh, NC, USA

B. Busser
Grenoble University Hospital
Grenoble, France

Hugh Byrne
FOCAS Institute, Dublin Institute of Technology
Dublin, Ireland

Murali Chilkapati
Tata Memorial Centre
Mumbai, India

Minhaeng Cho
IBS/Korea University
Seoul, Korea

Daniel O. Cicero
University of Rome “Tor Nergata”
Rome, Italy

S. Cohen
Center for Biophysical Pathology, Rutgers-NJMS
NJ, USA

J.G. Contreras
Universidad Autónoma de San Luis Potosí
San Luis Potosí, Mexico

L. Davenport
Brooklyn College of CUNY, New York
NY, USA

Michael Davies
The Heart Research Institute
Sydney, Australia

Pavlina Dolashka
Bulgarian Academy of Sciences
Sofia, Bulgaria

Pavel Dorozhkin
NT-MDT Co.
Moscow, Russia

S. F. El-Mashtoly
Ruhr-University Bochum
Bochum, Germany

Marco Ferrari
University of L'Aquila
L'Aquila, Italy

Yuji Furutani
Institute for Molecular Science, JST PRESTO "Chemical conversion of light energy"
Myodaiji, Okazaki, Japan

Francisco Galindo
Universitat Jaume I de Castellón
Castellón de la Plana, Spain

Amir Gandjbakhche
National Institutes of Health
Bethesda, MD, USA

Peter Gardner
Manchester Institute of Biotechnology
University of Manchester
Manchester, UK

Klaus Gerwert
Lehrstuhl für Biophysik
Ruhr-Universität Bochum, Germany

N. Gierlinger
University of Natural Resources and Applied Sciences
Vienna, Austria

Elisabetta Giorgini
Polytechnic University of Marche
Italy

Kristine Glunde
Johns Hopkins University School of Medicine
Baltimore, MD, USA

Juan Carmelo Gomez-Fernandez
Universidad de Murcia
Murcia, Spain

Duncan Graham
University of Strathclyde
Glasgow, UK

J.-X. Guo
The First Affiliated Hospital of Xi'an JiaoTong University
Xi'an, China

Abigail Haka
Cornell University
Ithaca, NY, USA

Takafumi Hamaoka
Faculty of Sport and Health Science, Ritsumeikan University
Kusatsu, Shiga, Japan

Stavros Hamodrakas
Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens
Athens, Greece

Ruquan Han
Beijing Tiantan Hospital, Capital Medical University
Beijing, China

Hans Hebert
Karolinska Institutet
Huddinge, Sweden

Elizabeth Hillman
Columbia University
New York, NY, USA

Hoi-Ying Holman
Lawrence Berkeley National Laboratory
Berkeley, CA, USA

Zhiwei Huang
National University of Singapore
Singapore

Haruto Ishikawa
Biophysical Chemistry Lab., Department of Chemistry, Graduate School of Science, Osaka University
Toyonaka, Osaka, Japan

N.R. Jagannathan
All India Institute of Medical Sciences
New Delhi, India

Risto Kauppinen
University of Bristol
Bristol, UK

Eamonn Kennedy
University College
Dublin, Ireland

Johann Klare
University of Osnabrück
Osnabrück, Germany

K. Kneipp
Technical University of Denmark
Lyngby, Denmark

Wolfgang Knoll
Austrian Institute of Technology
Vienna, Austria

Hisataka Kobayashi
National Cancer Institute
Bethesda, MD, USA

Z. Kóta
Biological Research Centre, Hungarian Academy of Sciences
Szeged, Hungary

Christoph Kraft
Friedrich-Schiller-Universität Jena
Jena, Germany

M. Krishna
Chilakapati Laboratory, ACTREC, Tata Memorial Center
Navi Mumbai, India

Cristina Kurachi
São Carlos Institute of Physics, University of São Paulo, São Carlos
São Paulo, Brazil

Jeongkyu Lee
University of Bridgeport
USA

Bernhard Lendl
Institute of Chemical Technologies and Analytics, Division Environmental and Process Analytics, Vienna University of Technology
Vienna, Austria

Jianjun Li
National Research Council
Ottawa, Canada

Shan-Yang Lin
Yuanpei University
Hsinchu, Taiwan

Hong Liu
University of Oklahoma
Norman, OK, USA

H. Peter Lu
Bowling Green State University
OH, USA

Qing Lu
Shanghai Renji Hospital
Shanghai, China

Sandra Luber
University of Zurich
Switzerland

A. Macnab
University of British Columbia
Vancouver, Canada

M.P. Marques
University of Coimbra
Coimbra, Portugal

Airton Martin
Laboratório de Espectroscopia Vibracional Biomédica – LEVB, Instituto de Pesquisa e Desenvolvimento - IPD, Universidade do Vale do Paraíba – UNIVAP, Urbanova, São José dos Campos
São Paulo, Brazil

Koichi Matsuo
Hiroshima Synchrotron Radiation Center, Hiroshima University
Higashi-Hiroshima, Japan

James M. McDonnell
Kings College London
London, UK

Lisa M. Miller
Brookhaven National Laboratory
Upton, NY, USA

Konstantin Momot
Queensland University of Technology
Brisbane, Australia

Cristina Muntean
National Institute for Research and Development of Isotopic and Molecular Technologies
Cluj-Napoca, Romania

D. Naumann
Robert Koch Institute
Berlin, Germany

Takumi Noguchi
|Nagoya University
Nagoya, Japan

S.J. Perkins
University College London
London, UK

Ronei J. Poppi
University of Campinas
Campinas, Brazil

Hidetoshi Sato
Kwansei Gakuin University
Hyogo, Japan

F. Severcan
İstanbul Kemerburgaz University
Istanbul, Turkey

Zhifeng Shao
Shanghai Jiao Tong University
Shanghai, China

Jun Shen
National Institute of Mental Health, Magnetic Resonance Spectroscopy Unit, Mood and Anxiety Disorders Program, NIMH
Bethesda, MD, USA

Hideyuki Shinzawa
Nagoya University
Nagoya, Japan

Pranav Shrivastav
Department of Chemistry, School of Sciences, Gujarat University
Ahmedabad, India

Stavros Sifakis
University Hospital of Heraklion
Crete, Greece

Lorna Smith
University of Oxford
Oxford, UK

Gregory Stephanopoulo
MIT, Cambridge
MA, USA

L. Sun
Research Center of Nano Science and Technology, Shanghai University
China

Tom Sutherland
Central Melbourne Medical Imaging
Melbourne, Australia

Fabio Tanfani
Università Politecnica delle Marche
Ancona, Italy

Keisuke Tominaga
Kobe University
|Kobe, Japan

Hans Vogel
University of Calgary
Calgary, Canada

W. F. Wolkers
Leibniz Universitaet
Hannover, Germany

Ed X. Wu
University of Hong Kong
Hong Kong, China

Gilwon Yoon
Seoul National University of Science and Technology
Seoul, South Korea

Zhiwu Yu
University of Saskatchewan
Saskatoon, Canada

Haishan Zeng
University of British Columbia
Vancouver, Canada

Denise Zezell
Laboratory of Biophotonics, Center for Lasers and Applications, IPEN-CNEN/SP, Cidade Universitária
São Paulo, Brazil

Jin Zhang
University of California
Santa Cruz, CA, USA

G. Zhu
The Hong Kong University of Science and Technology
Hong Kong, China

Author Guidelines

SUBMISSION OF MANUSCRIPT

By submitting my article to this journal, I agree to the Author Copyright Agreement, the IOS Press Ethics Policy, and the IOS Press Privacy Policy.

Authors are requested to submit their manuscript electronically to journal’s Editorial Management system. 
Note that the manuscript should be uploaded as one file with tables and figures included. This file can be a Word document, a PDF, or a zip file.

Please contact the Editorial Office if you experience difficulties with the online system.

Required files
For initial submission a .pdf file of the article is sufficient. After an article has been accepted for publication an editable file of the text, such as MsWord or LateX, is required. If you are uploading a paper that has been accepted for publication or accepted pending minor revisions please upload the source files of the paper. If using LaTeX please use our LaTeX template and also send a pdf version of the LaTeX file as well as separate files of all figures (if any); see "Preparation of manuscripts" for the required file formats. LaTeX packages should be compiled into .zip or .rar files.

Colour figures
It is possible to have figures printed in colour, provided the cost of their reproduction is paid for by the author. See Preparation of Manuscripts for the required file formats.

OPEN ACCESS MANDATES

A growing number of funding agencies now require that research articles they have funded must be made Open Access. This may be either by mandating deposit in repositories after an embargo period or by stipulating that research is published as Open Access. Publishing in this journal complies with all major funding agency requirements.

Gold Open Access Publishing (Open Access Option)
The Open Access option helps authors to comply with major funder mandates. This option allows authors the choice of paying a fee to make their article publicly available on the journal’s website immediately upon publication. The publisher will also deposit the final, published version of the Open Access article into PubMed Central immediately upon publication. All Open Access articles are published under the terms of the Creative Commons Attribution Non-Commercial License.

If requested by the author, Research Councils UK (RCUK) and Wellcome Trust funded Open Access articles will be published under the terms of the Creative Commons Attribution License (CC-BY). After acceptance of their article, the author should send a separate message to the publisher at w.van.der.sluijs@iospress.nl to notify that their article (include reference number) should be published Open Access under the RCUK mandate. An extra fee applies for CC-BY publications.

Green Open Access Publishing (Self-Archiving)
Authors who do not select Open Access publication may self-archive and post the final manuscript version on their own institution, company or funding agency repositories immediately upon acceptance. Authors that are funded by the NIH, Research Councils UK (RCUK) and Wellcome Trust are welcome to deposit their final manuscript version to PubMed Central (Submission Method C) and Europe PubMed Central immediately upon acceptance. In all cases a publication reference and URL to the journal’s website must be provided on the first page of the manuscript.

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PREPARATION OF MANUSCRIPTS

Organization of the paper and style of presentation
Manuscripts must be written in English. Authors whose native language is not English are advised to consult a professional English language editing service or a native English speaker prior to submission.

A list of 5 potential reviewers should be provided along with the manuscript. The reviewers should not have a conflict of interest with any of the authors.

Manuscripts should be prepared with wide margins and double spacing throughout, including the abstract, footnotes and references. Every page of the manuscript, including the title page, references, tables, etc., should be numbered. However, in the text no reference should be made to page numbers; if necessary, one may refer to sections. Try to avoid the excessive use of italics and bold face.

Manuscripts should be organized in the following order:

  • Title page
  • Body of text (divided by subheadings)
  • Acknowledgements
  • References
  • Tables
  • Figure captions
  • Figures

Headings and subheadings should be numbered and typed on a separate line, without indentation.

SI units should be used, i.e., the units based on the metre, kilogramme, second, etc. 

Title page
The title page should provide the following information:

  • Title (should be clear, descriptive and not too long)
  • Name(s) of author(s); please indicate who is the corresponding author
  • Full affiliation(s)
  • Present address of author(s), if different from affiliation
  • Complete address of corresponding author, including tel. no., fax no. and e-mail address
  • Abstract
  • Keywords

If any author is also a member of the Biomedical Spectroscopy and Imaging Editorial Board, this should be declared in the Conflict of Interest section.

Abstract
The abstract should be clear, descriptive, self-explanatory and not longer than 200 words, it should also be suitable for publication in abstracting services.
The abstract for research papers should follow the “structured abstract” format. Section labels should be in bold uppercase letters followed by a colon, and each section will begin on a new line.
BACKGROUND:
OBJECTIVE:
METHODS:
RESULTS:
CONCLUSIONS:

Tables
Number as Table 1, Table 2 etc, and refer to all of them in the text.
Each table should be provided on a separate page of the manuscript. Tables should not be included in the text.
Each table should have a brief and self-explanatory title.
Column headings should be brief, but sufficiently explanatory. Standard abbreviations of units of measurement should be added between parentheses.
Vertical lines should not be used to separate columns. Leave some extra space between the columns instead.
Any explanations essential to the understanding of the table should be given in footnotes at the bottom of the table.

Policy on Conflicts of Interest
For Authors
Biomedical Spectroscopy and Imaging requires authors to declare all conflicts of interest, financial or otherwise, independent of relevance to the particular manuscript. All authors must submit a conflicts of interest statement. If there is no conflict of interest to declare, include this section with the statement "The authors have no conflict of interest to report". Conflicts of interest are herein defined as factors or relationships that could be seen to compromise (or impact) the impartiality of the authors of an article.

If an author is also on the Editorial Board of this journal, the following statement should be included in this section: "<AUTHOR> is an Editorial Board member of this journal, but was not involved in the peer-review process nor had access to any information regarding its peer-review."

For Referees
Biomedical Spectroscopy and Imaging requests that referees with conflicts of interest, financial or otherwise, declare them when submitting their report and recuse themselves when there is a conflict that may impact a fair and impartial review.

In-house submissions are subjected to the peer review process described above. Members of the Editorial Board of Biomedical Spectroscopy and Imaging are not involved in any way with the peer review process of articles on which they are authors.

Examples
Financial conflicts of interest:
These can include any financial relationship between the authors and any organization that may have a financial interest in their research or financial interests on the part of the authors themselves. This can include, but is not limited to, employment, stocks or shares, patents, research funding, travel or other expenses, lecture fees, or goods or services. Authors should disclose any such relationships: past 2 years, present or anticipated along with any role these organizations may have had in the design, execution or presentation of the study. These can also include financial interests on the part of the authors themselves, such as stocks or shares, patents, or other forms of financial gain.

Non-financial conflicts of interest:
These can include any relationship between the authors and any person or organization that could reasonably be seen to compromise (or impact) the impartiality of the authors of an article. This can include, but is not limited to benefits to relatives, close friends or associates, or organizations that the author has an unpaid relationship with (such as consulting or advisory roles, or providing administrative assistance).

References
Place citations as numbers in square brackets in the text. All publications cited in the text should be presented in an alphabetical list of references at the end of the manuscript in the following style:

[1] B. Newman and E.T. Liu, Perspective on BRCA1, Breast Disease 10 (1998), 3-10.
[2] D.F. Pilkey, Happy conservation laws, in: Neural Stresses, J. Frost, ed., Controlled Press, Georgia, 1995, pp. 332-391.
[3] E. Wilson, Active vibration analysis of thin-walled beams, Ph.D. Dissertation, University of Virginia, 1991.

Footnotes
Footnotes should only be used if absolutely essential. In most cases it is possible to incorporate the information in the text.
If used, they should be numbered in the text, indicated by superscript numbers and kept as short as possible. 

Figures
Number figures as Fig. 1, Fig. 2, etc and refer to all of them in the text.
Each figure should be provided on a separate sheet. Figures should not be included in the text.
Colour figures can be included, provided the cost of their reproduction is paid for by the author.
For the file formats of the figures please take the following into account:

  • Line art should be have a minimum resolution of 600 dpi, save as EPS or TIFF
  • Grayscales (incl photos) should have a minimum resolution of 300 dpi (no lettering), or 500 dpi (when there is lettering); save as tiff
  • Do not save figures as JPEG, this format may lose information in the process
  • Do not use figures taken from the Internet, the resolution will be too low for printing
  • Do not use colour in your figures if they are to be printed in black & white, as this will reduce the print quality (note that in software often the default is colour, you should change the settings)
  • For figures that should be printed in colour, please send a CMYK encoded EPS or TIFF

Figures should be designed with the format of the page of the journal in mind. They should be of such a size as to allow a reduction of 50%.
On maps and other figures where a scale is needed, use bar scales rather than numerical ones, i.e., do not use scales of the type 1:10,000. This avoids problems if the figures need to be reduced.
Each figure should have a self-explanatory caption. The captions to all figures should be typed on a separate sheet of the manuscript.
Photographs are only acceptable if they have good contrast and intensity.

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Quoting from other publications
Authors, when quoting from someone else's work or when considering reproducing figures or tables from a book or journal article, should make sure that they are not infringing a copyright. Although in general authors may quote from other published works, permission should be obtained from the holder of the copyright if there will be substantial extracts or reproduction of tables, plates, or other figures. If the copyright holder is not the author of the quoted or reproduced material, it is recommended that the permission of the author should also be sought. Material in unpublished letters and manuscripts is also protected and must not be published unless permission has been obtained. Submission of a paper will be interpreted as a statement that the author has obtained all the necessary permission. A suitable acknowledgement of any borrowed material must always be made.

IOS Pre-press
This journal publishes all its articles in the IOS Press Pre-Press module. By publishing articles ahead of print the latest research can be accessed much quicker. The pre-press articles are the corrected proof versions of the article and are published online shortly after the proof is created and author corrections implemented. Pre-press articles are fully citable by using the DOI number. As soon as the pre-press article is assigned to an issue, the final bibliographic information will be added. The pre-press version will then be replaced by the updated, final version.

PROOFS

The corresponding author will receive a PDF proof and is asked to check this proof carefully (the publisher will execute a cursory check only). Corrections other than printer's errors, however, should be avoided. Costs arising from such corrections will be charged to the authors. 

PURCHASES 

How to order reprints, a PDF file, journals, or IOS Press books
The corresponding author of a contribution to the journal will receive a complimentary PDF Author’s Copy of the article, unless otherwise stated. This PDF copy is watermarked and for personal use only. A free PDF copy will not be provided for conference proceedings and abstract issues. An order form for a PDF file without watermark, reprints or additional journal copies will be provided along with the PDF proof.

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An author is entitled to 25 % discount on IOS Press books. See Author's discount (25%) on all IOS Press book publications.

ETHICS POLICIES AND PATIENT PERMISSIONS

Procedures involving experiments on human subjects should be in accord with the ethical standards of the Committee on Human Experimentation of the institution in which the experiments were done or in accord with the Helsinki Declaration of 1975. The author must state compliance in the cover letter and in the Methods section of the article.

Procedures involving experimentation on animal subjects should be in accord with either the guide of the institution in which the experiments were done, or with the National Research Council’s guide for the care and use of laboratory animals. The author must state compliance in the cover letter and in the Methods section of the article.

Preferably patients in figures should be unrecognizable. Authors are responsible for obtaining patient permission for use of the material from all recognizable participants in photographs, videos, or other information that may be published in the Journal or on the journal’s website. A statement that permission was granted by the patient must accompany the figure legend. Do not use study participants' names, initials, hospital numbers, or other personal health information anywhere in the manuscript (including figures).

KUDOS

Authors of published articles (non-prepress, final articles) will be contacted by Kudos. Kudos is a service that helps researchers maximize the impact and visibility of their research. It allows authors to enrich their articles with lay metadata, add links to related materials and promote their articles through the Kudos system to a wider public. Authors will receive no more than three emails: one invitation and a maximum of two reminders to register for the service and link the published article to their profile. Using and registering for Kudos remains entirely optional. For more information, please have a look at our authors section.

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Abstracted/Indexed in

Cabell's Guide or Directory
Chemical Abstracts Service (CAS)
Embase
EVISA - European Virtual Institute for Speciation Analysis
Google Scholar

PubsHub
Web of Science: Emerging Sources Citation Index

Open Access

By default, articles published in Biomedical Spectroscopy and Imaging are available only to institutions and individuals with access rights. However, the journal offers all authors the option to purchase open access publication for their article as part of the IOS Press Open Library. This means that the final published version will be freely available to anyone worldwide, indefinitely, under a Creative Commons license and without the need to purchase access to the article. This is also referred to as “gold” open access.

Gold open access pricing
Authors who choose gold open access publication will be subject to an article publication charge of € 1250 / US$ 1450 for publication under the CC BY-NC 4.0 license or € 1850 / US$ 2080 for publication under the CC BY 4.0 license. Pricing is exclusive of possible taxes. After an article is accepted for publication, the corresponding author will be informed regarding the open access option during the production stages, and will have the opportunity to purchase open access for their article. It could be that the open access fee of an article is waived completely due an institutional agreement IOS Press has with the corresponding authors' institution. Please check the institutional agreements page for details.

Green open access
Authors who do not make use of the gold open access option may still make their article freely available using self-archiving, also referred to as green open access. Authors may make their final accepted manuscript available for free download from their personal or institutional website or institutional archive. This model is free for the author.

Social Media & Mailings: BSI is on Twitter, with social media editor Eid Brima at the helm. Be sure to follow us and be part of the conversation! If you do not already receive the BSI newsletter, we invite you to sign up to receive notification of new BSI issues, plus other related news. Sign up via this link tiny.cc/BSIsignup. You can read a sample newsletter here.

Emerging Sources Citation Index: Biomedical Spectroscopy and Imaging is covered in the Emerging Sources Citation Index in the Web of Science, which will provide greater discoverability for BSI articles leading to measurable citations.

Ranking: We are happy to announce that BSI has been ranked in the Google Scholar Metrics top 20 of spectroscopy journals.

Book series: Advances in Biomedical Spectroscopy is a book series that complements the journal Biomedical Spectroscopy and Imaging (BSI). This book series is devoted to in-depth discussion of specific spectroscopic and imaging techniques. Latest advances in the application and development of these methods in health, life and biomedical sciences are covered. The books are intended to serve the needs of experienced scientists and early stage researchers in both academia and industry. See here for more information.

Sustainable Development Goals

The content of this journal relates to SDG:

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Visit the SDG page for more information.