Bio-Medical Materials and Engineering

Impact Factor


35, 6 issues

Latest issue

35:3 online 14 May 2024

Next issue

35:4 scheduled for July 2024

Back volumes

From volume 1, 1991

ISSN print


ISSN online


Aims & Scope

The aim of Bio-Medical Materials and Engineering is to promote the welfare of humans and to help them keep healthy. This international journal is an interdisciplinary journal that publishes original research papers, review articles and brief notes on materials and engineering for biological and medical systems. Articles in this peer-reviewed journal cover a wide range of topics, including, but not limited to: Engineering as applied to improving diagnosis, therapy, and prevention of disease and injury, and better substitutes for damaged or disabled human organs; Studies of biomaterial interactions with the human body, bio-compatibility, interfacial and interaction problems; Biomechanical behavior under biological and/or medical conditions; Mechanical and biological properties of membrane biomaterials; Cellular and tissue engineering, physiological, biophysical, biochemical bioengineering aspects; Implant failure fields and degradation of implants. Biomimetics engineering and materials including system analysis as supporter for aged people and as rehabilitation; Bioengineering and materials technology as applied to the decontamination against environmental problems; Biosensors, bioreactors, bioprocess instrumentation and control system; Application to food engineering; Standardization problems on biomaterials and related products; Assessment of reliability and safety of biomedical materials and man-machine systems; and Product liability of biomaterials and related products.

Editorial Board


A. Toshimitsu Yokobori, Jr.
Professor Emeritus of Tohoku University
Specially Appointed Professor of Teikyo University
Advanced Comprehensive Research Organization (ACRO)
Teikyo University
2-22-1 Kaga Itabashi-ku
Tokyo, Japan

Founding Editor

Takeo Yokobori

Honorary Editors

Takeo Yokobori
William Bonfield
Edmund Y.S. Chao
Joon B. Park
Yukihiko Nosé

Editorial Advisory Board

Hideki Aoki
International Apatite Institute
Tokyo, Japan

Kenzo Asaoka
University of Tokushima 
Tokushima, Japan

Dan L. Bader
Queen Mary and Westfield College
London, United Kingdom

Joseph C. Barbenel
University of Strathclyde 
Glasgow, United Kingdom

Paul Calvert
University of Massachusetts
Dartmouth, MA, USA

Jiang Chang
Chinese Academy of Science
Shanghai, China

Ulrich M. Gross
Free University of Berlin
Berlin, Germany

Parvez I. Haris
De Montfort University
Leicester, United Kingdom

Yoshito Ikada
Kyoto University
Kyoto, Japan

Soichiro Itoh
Tokyo Medical and Dental University
Tokyo, Japan

Helen Kambic
The Cleveland Clinic Foundation
Cleveland, OH, USA

Dai Kawahara
Institute of Clinical Materials
Osaka, Japan

Masanori Kikuchi
National Institute for Materials Science
Tsukuba, Japan

Jack E. Lemons
University of Alabama
Tuscaloosa, AL, USA

Kimiko Makino
Tokyo University of Science
Chiba, Japan

Yoshinori Mitamura
Hokkaido University
Sapporo, Japan

Yoshinori Miyasaka
Senen General Hospital
Rifu, Japan

Egon Nordström
Abo Akademi University
Abo, Finland

Toshiro Ohashi
Hokkaido University 
Sapporo, Japan

Makoto Otsuka
Musashino University
Nishi-Tokyo, Japan

Hiroshi Ozawa
Tohoku Medical and Pharmaceutical University
Sendai, Japan

Kazuhide Ozeki
Tokyo Denki University
Saitama, Japan

Joseph M. Price
Faegre & Benson 
Minneapolis, MN, USA

Makoto Sakamoto
Niigata University
Niigata, Japan

Hirotaka Sano
Sendai City Hospital
Sendai, Japan

Amulya K. Saxena
Imperial College
London, United Kingdom

Tamotsu Tamaki
Nippon Institute of Technology
Saitama, Japan

Yuji Tanabe
Niigata University
Niigata, Japan

Tetsuya Tateishi
Ibaraki, Japan

Mitsugu Todo
Kyushu University
Fukuoka, Japan

Silvia Todros
University of Padova
Padova, Italy

Jaroslav Valenta
Czech Technical University
Prague, Czech Republic

Julian F.V. Vincent
The University of Reading
Reading, United Kingdom

Hiroki Watanabe
Kyoto Prefectural University
Kyoto, Japan

Kunihiro Yamashita
Tokyo Medical and Dental University
Tokyo, Japan

Author Guidelines


By submitting my article to this journal, I agree to the Author Copyright Agreement, the IOS Press Ethics Policy, and the IOS Press Privacy Policy.

Authors are requested to submit their manuscript electronically to the journal's editorial management system.

Publication fee
For articles that are submitted and accepted from 1 January 2023, authors will be required to pay a publication fee of €450/US$450.

A waiver request for the publication fee should be submitted before the initial submission of a paper. Please send your title, abstract, keyword list and author list including affiliations (and if available ORCID IDs) to the Editor-in-Chief, along with your motivation for the waiver. Your request will be evaluated by the editorial office.

Changes to authorship
Please note that changing the authors list (i.e. adding / removing authors, or changing the order) is not allowed after submission of the manuscript, unless the journal editor and all co-authors are informed and are in agreement with this change. Please see the IOS Press authorship policy for further information.

Artificial intelligence policy
Text generated from artificial intelligence (AI), machine learning, or similar algorithmic tools cannot be the original content in papers submitted to the journal. Nor does the journal accept figures, images, or graphics produced by such tools. However, AI tools can be used in the writing process to improve the readability and language. A disclosure should be added to the paper in case AI tools were used.

AI programs should not be included in the author list, nor should they be cited. The authors are ultimately responsible for the contents of the paper. For more information, see the IOS Press Ethics Policy.


Organization of the paper and style of presentation
Manuscripts must be written in English. Authors whose native language is not English are advised to consult a professional English language editing service or a native English speaker prior to submission.

Manuscripts should be prepared with wide margins and double spacing throughout, including the abstract, footnotes and references. Every page of the manuscript, including the title page, references, tables, etc., should be numbered. However, in the text no reference should be made to page numbers; if necessary, one may refer to sections. Try to avoid the excessive use of italics and bold face.

Manuscripts should be organized in the following order:

  • Title page
  • Body of text (divided by subheadings)
  • References
  • Tables
  • Figure captions
  • Figures
  • Headings and subheadings should be numbered and typed on a separate line, without indentation.

    SI units should be used, i.e., the units based on the metre, kilogramme, second, etc.

    Title page
    The title page should provide the following information:

  • Title (should be clear, descriptive and not too long)
  • Name(s) of author(s); please indicate who the corresponding author is 
  • Full affiliation(s)
  • Present address of author(s), if different from affiliation
  • Complete address of corresponding author, including e-mail address
  • Abstract
  • Keywords
  • Abstract
    The abstract should be clear, descriptive, self-explanatory and not longer than 200 words, it should also be suitable for publication in abstracting services.
    The abstract for research papers should follow the “structured abstract” format. Section labels should be in bold uppercase letters followed by a colon, and each section will begin on a new line.

    Materials and methods
    Ethical considerations
    Please include an explicit statement in the materials and methods section that procedures involving experiments on human subjects are done in accord with the ethical standards of the Committee on Human Experimentation of the institution in which the experiments were done or in accord with the Declaration of Helsinki of 1964 and its later amendments or comparable ethical standards. When experimental animals are used, the materials and methods section must briefly but explicitly state measures which were taken to minimize pain or discomfort, e.g. type and dose of anaesthetic used. Experiments should be carried out in accord with either the guide of the institution in which the experiments were done, or with the European Communities Council Directive of 24 November 1986 (86/609/EEC) or the Guidelines laid down by the NIH in the US.

    The approval number of the Ethics Committee or the institutional review board and its affiliation together with the date of approval, or alternative identifiers, must be added as part of the statement. Studies exempt from Institutional Review Board approval should report the reason for exemption, e.g. “This study, as a literature review, is exempt from Institutional Review Board approval”. Editors reserve the right to reject papers if there is doubt whether appropriate procedures have been used.

    Informed consent
    Patients have a right to privacy that should not be infringed without informed consent. Identifying information, including patients' names, initials, or hospital numbers, should not be published in written descriptions, photographs, and pedigrees unless the information is essential for scientific purposes and the patient (or parent or guardian) gives written informed consent for publication. Informed consent for this purpose requires that a patient who is identifiable should be shown the manuscript before it is published. When informed consent has been obtained it should be indicated in the Methods section.

    Reporting guidelines
    Manuscripts should adhere to the EQUATOR Network reporting guidelines relevant to the research design.

    Specify the acknowledgements. If there are none, you can still include this section and insert "The authors have no acknowledgments".

    Conflict of interest
    Statement of any potential conflicts should be clearly identified at the end of the paper. If there is no conflict of interest to declare, you must still include this section and insert the following statement: "The authors declare that they have no conflict of interest.".

    Specify sources of funding. If there are none, you can still include this section at the end of the paper and insert "The authors report no funding".

    Number figures as Fig. 1, Fig 2, etc. and refer to all of them in the text.
    Color figures can be included in the print version, provided the cost of their reproduction is paid for by the author. The online version has no extra charges for color figures.

    For the file formats of the figures please take the following into account:
    - line art should be have a minimum resolution of 600 dpi, save as EPS or TIFF
    - grayscales (including photos) should have a minimum resolution of 300 dpi (no lettering), or 500 dpi (when there is lettering); save as tiff
    - do not save figures as JPEG, this format may lose information in the process
    - do not use figures taken from the Internet, the resolution will be too low for printing
    - do not use color in your figures if they are to be printed in black & white, as this will reduce the print quality (note that in software often the default is color, you should change the settings)
    - for figures that should be printed in color, please send a CMYK encoded EPS or TIFF
    Figures should be designed with the format of the page of the journal in mind. They should be of such a size as to allow a reduction of 50%

    On maps and other figures where a scale is needed, use bar scales rather than numerical ones, i.e., do not use scales of the type 1:10,000. This avoids problems if the figures need to be reduced.
    Each figure should have a self-explanatory caption. The captions to all figures should be typed on a separate sheet of the manuscript.
    Photographs are only acceptable if they have good contrast and intensity.

    Number as Table 1, Table 2 etc, and refer to all of them in the text.
    Each table should be provided on a separate page of the manuscript. Tables should not be included in the text.
    Each table should have a brief and self-explanatory title.
    Column headings should be brief, but sufficiently explanatory. Standard abbreviations of units of measurement should be added between parentheses.
    Vertical lines should not be used to separate columns. Leave some extra space between the columns instead.
    Any explanations essential to the understanding of the table should be given in footnotes at the bottom of the table.


    Authors are requested to use the Vancouver citation style. Place citations as numbers in square brackets in the text. All publications cited in the text should be presented in a list of references at the end of the manuscript. List the references in the order in which they appear in the text. Only articles published or accepted for publication should be listed in the reference list. Submitted articles can be listed as (author(s), unpublished data). If an article has a DOI, this should be provided after the page number details. The number is added after the letters 'doi'. Manuscripts will not be considered if they do not conform to the Vancouver citation guidelines.

    Examples of the Vancouver style:

    [1] Rose ME, Huerbin MB, Melick J, Marion DW, Palmer AM, Schiding JK, et al. Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury. Brain Res. 2002; 935(12): 406.
    [2] Murray PR, Rosenthal KS, Kobayashi GS, Pfaller MA. Medical microbiology. 4th ed. St. Louis: Mosby; 2002.
    [3] Berkow R, Fletcher AJ, editors. The Merck manual of diagnosis and therapy. 16th ed. Rahway (NJ): Merck Research Laboratories; 1992.
    [4] Meltzer PS, Kallioniemi A, Trent JM. Chromosome alterations in human solid tumors. In: Vogelstein B, Kinzler KW, editors. The genetic basis of human cancer. New York: McGrawHill; 2002. p. 93113.
    [5] Canadian Cancer Society [homepage on the Internet]. Toronto: The Society; 2006 [updated 2006 May 12; cited 2006 Oct 17]. Available from:


    Copyright of your article
    Authors submitting a manuscript do so on the understanding that they have read and agreed to the terms of the IOS Press Author Copyright Agreement.

    Article sharing
    Authors of journal articles are permitted to self-archive and share their work through institutional repositories, personal websites, and preprint servers. Authors have the right to use excerpts of their article in other works written by the authors themselves, provided that the original work is properly cited. The consent for sharing an article, in whole or in part, depends on the version of the article that is shared, where it is shared, and the copyright license under which the article is published. Please refer to the IOS Press Article Sharing Policy for further information.

    Quoting from other publications
    Authors, when quoting from someone else's work or when considering reproducing figures or tables from a book or journal article, should make sure that they are not infringing a copyright. Although in general authors may quote from other published works, permission should be obtained from the holder of the copyright if there will be substantial extracts or reproduction of tables, plates, or other figures. If the copyright holder is not the author of the quoted or reproduced material, it is recommended that the permission of the author should also be sought. Material in unpublished letters and manuscripts is also protected and must not be published unless permission has been obtained. Submission of a paper will be interpreted as a statement that the author has obtained all the necessary permission. A suitable acknowledgement of any borrowed material must always be made.


    The corresponding author will receive a PDF proof and is asked to check this proof carefully (the publisher will execute a cursory check only). Corrections other than printer's errors, however, should be avoided. Costs arising from such corrections will be charged to the authors.

    The corrected proof is published online in the journal’s pre-press module and is indexed by PubMed where it appears as [Epub ahead of Print]. This is not the final version. When the article is published in an issue, the final published version replaces the pre-press file. Pre-press articles are fully citable by using their DOI number.


    How to order reprints, a PDF file, journals, or IOS Press books
    The corresponding author of a contribution to the journal will receive a complimentary PDF Author’s Copy of the article, unless otherwise stated. This PDF copy is watermarked and for personal use only. A free PDF copy will not be provided for conference proceedings and abstract issues. An order form for a PDF file without watermark, reprints or additional journal copies will be provided along with the PDF proof.

    If you wish to order reprints of an earlier published article, please contact the publisher at for a quotation.

    An author is entitled to 25 % discount on IOS Press books. See Author's discount (25%) on all IOS Press book publications.


    Authors of published articles (non-prepress, final articles) will be contacted by Kudos. Kudos is a service that helps researchers maximize the impact and visibility of their research. It allows authors to enrich their articles with lay metadata, add links to related materials and promote their articles through the Kudos system to a wider public. Authors will receive no more than three emails: one invitation and a maximum of two reminders to register for the service and link the published article to their profile. Using and registering for Kudos remains entirely optional. For more information, please have a look at our authors section.


    Would you like some pointers on how to help your research achieve a wider reach and greater impact? Please consult our Promotional Toolkit for Authors for tips.

    Please visit the IOS Press Authors page for further information.

    Abstracted/Indexed in

    Academic Source Complete
    Applied Mechanics Reviews
    Cabell's Guide or Directory
    Cambridge Scientific Abstracts
    Ceramic Abstracts
    Chemical Abstracts Service (CAS)
    Corrosion Abstracts
    CSA Illumina
    EBSCO Databases
    Google Scholar
    Inspec IET
    Materials Business File - Steels Alerts
    Metals Abstracts/METADEX
    Microsoft Academic Search
    Science & Technology Collection
    Ulrich's Periodicals Directory
    Web of Science: Biological Abstracts
    Web of Science: BIOSIS Previews
    Web of Science: Journal Citation Reports/Science Edition
    Web of Science: Science Citation Index-Expanded (SciSearch®)

    Open access

    By default, articles published in Bio-Medical Materials and Engineering are available only to institutions and individuals with access rights. However, the journal offers all authors the option to purchase open access publication for their article as part of the IOS Press Open Library. This means that the final published version will be freely available to anyone worldwide, indefinitely, under a Creative Commons license and without the need to purchase access to the article. This is also referred to as “gold” open access.

    Gold open access pricing
    Authors who choose gold open access publication will be subject to an article publication charge of €1500 / US$1500 for publication under the CC BY-NC 4.0 license or €2150 / US$2150 for publication under the CC BY 4.0 license. Pricing is exclusive of possible taxes. After an article is accepted for publication, the corresponding author will be informed regarding the open access option during the production stages, and will have the opportunity to purchase open access for their article. It could be that the open access fee of an article is waived completely due an institutional agreement IOS Press has with the corresponding authors' institution. Please check the institutional agreements page for details.

    Green open access
    Authors who do not make use of the gold open access option may still make their article freely available using self-archiving, also referred to as green open access. Authors may make their final accepted manuscript available for free download from their personal or institutional website or institutional archive. This model is free for the author.

    PubMedCentral deposits
    This journal deposits all open access articles in PubMedCentral (PMC) as part of the IOS Press Open Library. If an author chooses to publish their paper with open access then the publisher will deposit the article in PMC upon publication.

    Peer Review Policy

    Bio-Medical Materials and Engineering is a peer-reviewed journal. Articles submitted to the journal undergo a single-blind peer review process. This means that the identity of the authors is known to the reviewers but the identity of the reviewers is not communicated to the authors. Please visit our reviewer guidelines for further information about how to conduct a review.

    After automatic plagiarism screening through iThenticate, all submitted manuscripts are subjected to initial appraisal by the Editor-in-Chief and, if found suitable for further consideration, to rigorous peer review by independent, anonymous expert referees. Reasons to reject a paper in the pre-screening process could for example be that the work does not fall within the aims and scope, the writing is of poor quality, the instructions to authors were not followed or the presented work is not novel.

    Papers deemed suitable to be reviewed will be assigned to a handling editor. The handling editor will then invite reviewers to comment on the work and might consider inviting the reviewers suggested by the author(s). Editors and reviewers are asked to excuse themselves from reviewing a submission if a conflict of interest makes them unable to make an impartial scientific judgment or evaluation. Conflicts of interest include but are not limited to: collaboration with the authors in the past three years; any professional or financial affiliations that may be perceived as a conflict of interest; a history of personal differences with the author(s).

    As a standard policy, decisions are based on two reviews, in some specific circumstances one review may be deemed sufficient to make a decision on a paper. The Editor-in-Chief strives to ensure a typical turnaround time of 3 months.

    Reviewers are asked to judge a paper on at least:

    • Logical, concise ordering of ideas
    • Use of sound research methods
    • Adequacy of documentation    
    • Material has good applied use in the field    
    • Readability and interest level

    Based on the received reviews the handling editor will propose to the Editor-in-Chief a recommendation:

    1. Accept article as submitted
    2. Accept article revision by the author according to suggestions made in review
    3. Revise and resubmit
    4. Reject
    5. Consider for another issue/publication

    They mean the following:

    1. The manuscript is suitable for publication and only requires minor polishing; thus, no further reviews are requested.
    2. The authors are required to make moderate changes to their manuscript. The manuscript becomes acceptable for publication if the changes proposed by the reviewers and editors are successfully addressed. The revised manuscript will be examined by the Editors-in-Chief and possibly sent back to all (or a selection of) reviewers for a second round of reviews. Authors are requested to provide a letter to the reviewers detailing the improvements made for the resubmission.
    3. In its current form, the manuscript is not suitable for publication. A resubmission would require substantial revisions and is only encouraged in special cases. The resubmitted manuscript will be considered as a new submission.
    4. The manuscript is rejected as it is deemed to be out of scope, not relevant, or not meeting the journal’s quality standards in terms of significance, novelty, and/or presentation.
    5. The manuscript is rejected as it is deemed to be better suited for a different journal or publication.

    Authors are notified by the Editorial Assistant (in name of the Editor-in-Chief), whose decision is final.

    Latest Articles

    Discover the contents of the latest journal issue:

    Customized design and biomechanical property analysis of 3D-printed tantalum intervertebral cages
    Shu Du, Yutao Zhang, Wurikaixi Aiyiti, Yong Teng, Ru Jia, Houfeng Jiang

    Rapidly degradable konjac glucomannan hydrogels cross-linked with olsalazine for colonic drug release
    Huili Fu, Qiao Zhang, Yunfei Zhang, Liang Li, Guoping Yan

    Subcutaneous tissue reaction to a novel nano zinc oxide eugenol dental cement
    Masitah Hayati Harun, Rohmat Nursin, Dasmawati Mohamad, Siti Khadijah Mohd Bakhori, Shahrom Mahmud

    Simvastatin-loaded 3D aerogel scaffolds promote bone regeneration
    Zhou Xiaowei, Lai Linfeng, Chen Xueqin, Zhu Xianfeng

    Study of the mechanism of action of sand therapy on atherosclerosis based on the two-phase flow-Casson model
    Wang Kun, Fu Rongchang, Wu Hui

    Sustainable Development Goals

    The content of this journal relates to SDG:

    sdg symbolsdg symbolsdg symbolsdg symbolsdg symbol

    Visit the SDG page for more information.

    jcr_2020_logo - kopie2.png